Believe it or not, Torin, this is usually not much of a problem, particularly if your floor is dry and in good shape. The easiest way to handle it is to nail furring strips to the joists and then staple acoustical tile to the furring strips. You might have to do some things to accommodate things like access areas for plumbing and HVAC ducts. Hopefully, you can box in the ducts and build shelves or something under them. Be sure that you do all the wiring for ceiling lights before you put up the tile and don't plan on ceiling fans. The furring strips and tile only uses about an inch and a half of height.